Tainted characters have their own set of completion marks and corresponding unlocks, albeit fewer than the original characters - a single unlock for both of the timed challenges ( Boss Rush and Hush), one for all of the main path bosses ( Isaac, ?, Satan, and The Lamb), and one for each endgame boss, excluding 'normal' Ultra Greed.Įach character's progress can be gauged by checking their completion marks.Įach character is unlocked by accomplishing a certain task in the game. Many have unique, game-changing mechanics, but often come with a corresponding drawback. Each tainted character maintains the same general theme as the original incarnation, but twisted or taken to an extreme. Repentance also added an alternate 'tainted' version of all 17 characters, unlockable in the expansion's final endgame area. Each character starts with different stats and abilities that give them their own unique playstyle. In the Repentance expansion, two characters ( Bethany and Jacob and Esau) were added. In the Afterbirth † expansion, one character ( Apollyon) was added, plus one more secret character ( The Forgotten) added via a Booster Pack. In the Afterbirth expansion, one new character ( Lilith) was added, plus one more character via an update ( Keeper). Rebirth contains four new characters ( Azazel, Lazarus, Eden, and The Lost). Eve was added in The Binding of Isaac's Halloween Update, while Samson was added in the Wrath of the Lamb expansion. Five of these characters ( Isaac, Magdalene, Cain, Judas, and ?) came with the original The Binding of Isaac, while two additional characters ( Eve and Samson) were added later. Spawns another Vurp! pill if no other pills were used yet.There are 34 playable characters in The Binding of Isaac: Rebirth, with 11 available in the base game and 23 available in the DLCs. Spawns a pool of black creep beneath Isaac The effect triggers again 30 seconds after use and again 60 seconds after use I'm excited!!! - Speeds up all enemies for the rest of the room. Slows all enemies for the rest of the current room Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row) Horf! - When used, shoots an Ipecac explosive shot. Unlocked from the 'Once more with the feeling!' achievement (complete a victory lap, defeating the lamb boss) Gulp! - When used will consume your current trinket, destroying it and giving you its effect permanently. Unlocked from the 'Sin Collector' achievement (collect every Bestiary entry) Unlocked from Challenge #25 - Have a Heartįeels like I'm walking on sunshine! - Turns Isaac invincible for a few seconds (similar to Unicorn Stump). ? - Gives the curse of the maze effect for the current floor. Happens a total of 3 times over 30 seconds Retro Vision - Pixelates the screen for a few seconds, obscuring your vision. Similar to Explosive Diarrhea but with poop Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect) Unlocked from Challenge #24 - PAY TO PLAY Percs - Causes Isaac to only take half a heart of damage from all sources for the current room (The Wafer effect). One makes you larger - Increases Isaac's size, but does not affect the size of his hitbox One makes you smaller - Reduces Isaac's size and hitbox size If there are no enemies this pill spawns 1-3 blue spiders instead Infested? - Spawns one blue attack spider for every enemy in the room. Infested! - Destroys all poops in the room and spawns a blue attack spider on every destroyed poop Unlocked from Challenge #24 - PAY TO PLAYįriends till the end - Spawns three friendly blue attack flies Lemon Party - Spawns a large yellow pool on the floor around you, damaging enemies which walk in itĪddicted - Causes you to take a full heart of damage for all sources for the current room. I found pills - Changes the appearance of Isaac's face for the current room (Cosmetic change only) I can see forever - Opens secret room and super secret room entrances on the current floor Hematemesis - Empties all but one red heart container and spawns 1-4 red hearts on the floor If you have 1 or less heart containers, this pill becomes Health Up Can be negated with Black Candleīad Gas - Isaac farts, poisoning enemies around himīombs are key - Switches number of bombs and keysĮxplosive Diarrhea - Spawns five live troll bombs behind Isaac, one per secondįull Health - Restores all your empty red heart containers Can be used with Placebo to generate infinite batteriesĪmnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). 48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups.
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